Neurodermatitis is an inflammatory skin disease that occurs in episodes. The most common symptoms are red, scaly skin and severe itching. Sometimes weeping eczema also appears on the skin. The disease progresses in episodes and has an individual appearance that depends on age. In most cases, the back of the knees, elbows, neck and wrists are affected. However, the face and trunk can also be affected.
Neurodermatitis is caused by a dysregulation of the immune system. This is manifested in an excessive immune response in which a certain group of antibodies, immunoglobulin E (Ig E), are produced in increased amounts. These Ig E ensure, among other things, that certain cells secrete substances that lead to an inflammatory reaction.
Many classic treatment methods, such as cortisone or light therapy, can only reduce the symptoms, but are often accompanied by corresponding side effects. However, the immunological cause of the disease remains.
Individual immunotherapy, on the other hand, directly addresses the dysregulation of the immune system. It can have a regulating effect on the immune system with the aim of bringing it back into balance and inhibiting the excessive release of antibodies. As a result, skin irritations can be significantly reduced or even disappear permanently.
The continuously optimized Individual Immunotherapy has already been applied in many thousands of cases. Especially in infants and children, excellent treatment results could be achieved with the urexent® therapy.
Together with neurodermatitis and asthma, allergies are a form of atopic diseases.
Allergies can manifest themselves in different forms. Symptoms range from allergic rhinitis, itchy and burning eyes and allergic asthma and skin reactions to gastrointestinal complaints.
The number of people suffering from allergies, particularly in industrialised countries, has doubled or tripled over the past three decades and is continuously trending upward.
An allergy is an overreaction of the immune system to non-infectious foreign substances (antigens or allergens). The body reacts with various signs of inflammation and the excessive production of antibodies, in particular those of the Ig-E type. People who are effected develop an intolerant reaction to one or more – usually harmless – foreign substances over time, such as flower pollen or dust mites.
The individual immunotherapy directly addresses the cause of the disease. It can have a regulating effect on the misdirected immune system and restore its balance. The excessive production of Ig-E is inhibited, the self-regulation of the immune system is supported and the susceptibility to allergies can decrease.
Bronchial asthma is a chronic, inflammatory disease of the respiratory tract and is classified as an atopic disease. Asthmatics have a permanent inflammation of the bronchial mucosa, which leads to hypersensitivity of the airways. The result is swelling of the mucous membrane and excessive secretion production, which constricts the bronchial tubes. In an acute asthma attack, the bronchial muscles also tighten (bronchospasm), which leads primarily to reduced exhalation. Shortness of breath, palpitations, and a constant urge to cough may be other symptoms. Bronchial asthma usually begins in childhood and is one of the most common chronic diseases at this stage of life.
Asthma is divided into two types, allergic and non-allergic asthma. Again and again, asthma sufferers are found to have connections to other allergies - sometimes as a cause in the first type and sometimes, therefore, in the second.
In asthma sufferers, the immune system is highly sensitized to various stimuli. These can be processes inside the body, e.g., infections, or stimuli caused by allergens from outside. The increased sensitivity to these triggers leads to increased production of inflammatory mediators, including immunoglobulin E (IgE). These interact with the specific antigen to cause the release of allergy- and inflammation-triggering messenger substances.
This is where Individual Immunotherapy comes in with the regulation and control of the immune system. By inhibiting the excessive release of antibodies, the inflammation of the bronchial tubes can be reduced.
Based on many years of experience with allergies and neurodermatitis, lasting success has been achieved with individual immunotherapy in asthma patients or in patients who have several of the above-mentioned forms of disease.
Psoriasis vulgaris is a chronic inflammatory disease of the skin with redness and severe dandruff. Psoriasis frequently leads to severe itching which can be very distressing for those affected.
Psoriasis is not contagious and it is believed that, amongst other things, a dysregulation of the body's defence system (immune system) plays a role in the pathogenesis. An uncontrolled proliferation of a specific type of immune cell called T-cells in the skin clearly plays a key role. These cells contribute to an increased release of certain messenger substances known as cytokines.
The regulation of the cytokine release cycle appears to be dysfunctional; within the scope of the autoimmune process, a persistent inflammatory response occurs in the skin and also results in a massive proliferation of epidermal cells (keratinocytes). The skin becomes thickened and scaly.
The individual immunotherapy addresses this misdirected process. Its goal is to restore the body's necessary tolerance processes so that its own structures are recognised normally and the balance between inflammatory responses and the healing process is restored and the complexion can be normalized.
Crohn's disease and ulcerative colitis are chronic inflammatory bowel diseases. The inflammation usually progresses in episodes and is characterized by abdominal pain and severe, often bloody diarrhea: ulcers or stenoses can often form.
Crohn's disease can occur in any section of the digestive tract, but most commonly affects the end of the small intestine (ileum) or the upper section of the large intestine (colon). In the disease, there is inflammation not only of the mucosa, but of all the wall layers of the intestine. In ulcerative colitis, on the other hand, there is inflammation and formation of ulcers in the rectum and colon.
Autoimmune processes, among others, are seen as triggers for inflammatory bowel disease. The immune system appears to be directed against its own body and thus causes permanent inflammation in the intestine. In many cases, the level of certain antibodies is increased and the formation of inflammatory mediators is pronounced.
This is where Individual Immunotherapy comes in. Through its regulating influence on the immune system, the excessive formation of antibodies can be reduced and the inflammatory reaction diminished.
Rheumatism refers to complaints of the musculoskeletal system, where tearing and pulling pain can severely restrict mobility. Rheumatic diseases affect not only bones and joints but also "soft" tissues such as muscles, ligaments or tendons (soft tissue rheumatism). Osteoarthritis, gout and lupus erythematosus are also rheumatic diseases.
Rheumatic diseases are divided into inflammatory and degenerative (wear and tear) diseases. The first group is considered to be autoimmune, i.e. the form of disease in which individual immunotherapy is used.
Due to a misdirected immune process, the cells that are normally responsible for defending against viruses, bacteria and fungi suddenly attack the body's own healthy tissue. In rheumatoid arthritis, for example, the most common form of inflammatory joint disease, the synovium is attacked and gradually destroyed.
The autologous immunotherapy starts with the regulation of the immune system and with a correction of the over and false reactions. Through the targeted preparation and manipulation of the body's own substances and their return to the body, the autoimmune reaction can be mitigated, and the symptoms reduced.